* 3 Cats over 27.5 lb. As I opened the packaging I split some on my hands. Discount flea, tick, heartworm and intestinal worm treatments by PetBucket. Foreign Market Experience: The following adverse events were reported voluntarily during post-approval use of the product in cats in foreign markets: polydipsia, swelling of chin and lips, periorbital swelling, blepharospasm, pruritus, erythema, aggression, agitation, pyrexia, mydriasis, hypersalivation, hyperactivity, alopecia, and excessive grooming. Fluralaner is an inhibitor of the arthropod nervous system. Part the fur at the administration site. In a pilot oral safety study, adult cats orally administered 0.5X or 1X the maximum labeled dose of Bravecto Plus had foaming hypersalivation for up to five minutes and reduced food consumption on the day of dosing. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Bravecto for Cats Medium Cats; Bravecto Plus - DO NOT USE. In a European field study for fluralaner topical solution for cats, there were three reports of facial dermatitis in humans after close contact with the application site which occurred within 4 days of application. ), More about getting RSS News & Updates from DailyMed, 2 0061-5997-02, 0061-5998-01, There were no clinically-relevant, treatment-related effects on physical examination, body weights, food consumption, or clinical pathology (hematology, clinical chemistries, coagulation tests, serum amyloid A, and urinalysis). Contents: 1 tube containing 250 mg fluralaner and 12.5 mg moxidectin Approved by FDA under NADA # 141-518, For cats and kittens 6 months of age and older Greasy, oily, or wet appearance may occur at the application site in some cats. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Labels, All Index In an oral safety study for fluralaner topical solution for cats, four out of six cats experienced coughing immediately after oral administration of the maximum labeled dose of 93.0 mg fluralaner/kg. If contact with eyes occurs, then flush eyes slowly and gently with water. Each milliliter contains 280 mg of fluralaner and 14 mg of moxidectin. Treated kittens had reduced food consumption on the day of treatment. Step 1: Immediately before use, open the pouch and remove the tube. Bravecto Plus is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment of infections with intestinal roundworm (Toxocara cati; 4th stage larvae, immature adults and adults) and hookworm (Ancylostoma tubaeforme; 4th stage larvae, immature adults and adults). Percentage of Cats with Adverse Reactions (AR) in the Field Study, Safety in cats infected with adult heartworm (Dirofilaria immitis), All Drug This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Margin of Safety Study: In a margin of safety study, Bravecto Plus was administered topically to 9- to 13-week-old (mean age 12 weeks) kittens at 1X, 3X, and 5X the maximum labeled dose of 93.0 mg fluralaner/kg and 4.7 mg moxidectin/kg at three, 8-week intervals (10 kittens per group). Wash hands and contacted skin thoroughly with soap and water immediately after use of the product. Doses of BRAVECTO® for dogs and BRAVECTO® for cats are counted separately and cannot be added together when determining rebate amounts. For cats, Bravecto® flea treatment is available as a topical solution, which is applied to your catâs skin on the back of their neck. Kills fleas, ticks, roundworms, hookworms and prevents heartworm disease for 2 months. Margin of Safety Study: In a margin of safety study, Bravecto Plus was administered topically to 9- to 13-week-old (mean age 12 weeks) kittens at 1×, 3×, and 5× the maximum labeled dose of 93.0 mg fluralaner/kg and 4.7 mg moxidectin/kg at three, 8-week intervals (10 kittens per group). After applying Bravecto for Cats, the medication quickly reaches tissue fluids under your cat's skin. If the product accidentally contacts skin and a sticky residue persists after washing, rubbing alcohol (70% isopropyl alcohol) can be applied to the area to remove the residue. In a well-controlled laboratory study, Bravecto Plus killed 100% of fleas within 12 hours after treatment and reduced the numbers of live fleas on cats by >99% within 12 hours after treatment or infestation for 2 months. DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. The cap should be rotated clockwise or counter clockwise one full turn. Keep this and all drugs out of the reach of children. published 4 months ago. If you are a consumer or patient please visit For prevention of heartworm disease, Bravecto Plus should be administered at 2-month intervals. How to use Bravecto Spot-on for Cats Ensure the animal's back is horizontal. In an oral safety study for fluralaner topical solution for cats, four out of six cats experienced coughing immediately after oral administration of the maximum labeled dose of 93.0 mg fluralaner/kg. Back horizontal during application, as per the diagram number of doses of BRAVECTO® for and... Information on more than 2 months in kittens less than twice the reference... 1: immediately before use, open flame or other sources of ignition the of. 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